Fascism Essay -- essays research papers

What is Fascism? Fascism is a 20th century form of nationalistic, militaristic, totalitarian dictatorship that seeks to create a feasible society through strict regimentation of national and individual lives. Total subordination to the service of the state and unquestioning loyalty to its leader would adjust conflicting interests. It is a modern political ideology that looks to regenerate the social, economic, and cultural life of a country by basing it on a heightened sense of national belonging of ethnic identity. Fascism rejects liberal ideas of freedom and individual rights, it often presses for the destruction of elections, legislatures and other elements of democracy. Despite fascism’s idealistic goals, attempts to build fascist societies have led to wars and persecutions that have caused millions of deaths (notably WWII and the Holocaust). As a result, fascism is strongly associated with right-wing fanaticism, racism, totalitarianism and violence. Fascist movements oppose such doctrines as liberalism, individualism, materialism, communism and conservatism. In general, fascists stand against all scientific, economic, religious, academic, cultural and leisure activities that do not serve their vision of a national political life. Fascism emphasised nationalism, but its appeal was international. Fascist political parties and movements capitalised on the intense patriotism that emerged as a response to widespread social and political uncertainty after World War I (1914-1918) and the Russian Revolution of 1917. It flourished between the so called fascist era of 1919 and 1945 in many countries mainly Italy, Germany, Spain and Japan. Even such liberal democracies as France and England had important fascist movements. Scholars disagree over how to define the basic elements of fascism, some even insist it was limited to Italy under Mussolini. When the term is capitalised as Fascism, it refers to the Italian movement. Beginning in the 1970’s, some scholars began to develop a broad definition of fascism and by the 1990’s many had embraced the new approach. This new approach emphasises the way in which fascist movements attempt revolutionary change and their central focus on popularising myths of ethnic or national renewal. Seen from this prospective, all forms of fascism have three common features: anticonservatism, a myth of national or ethnic renewal and ... ...vation less acutely than others.† All political parties except the fascists, were banned and trade unions were almost made illegal. Instead workers and employers were made to join â€Å"Corporations†, which were meant to sort out the differences between them. Newspapers and books were censored and all education was controlled. 1922 was renamed Year One and all school books were rewritten. Boys were expected to become good soldiers and all students were encouraged to join organisations which taught them how to be better fascists. Mussolini began a series of schemes to improve the Italian economy, he called these the â€Å"Battles.† He tried to make Italy self sufficient in food, farmers were encouraged to grow more wheat ( the Battle for Grain). Families were encouraged to have more children, the Battle for Births and land for agriculture was reclaimed, the Battle for Land. Women were discouraged from working horse riding and wearing trousers Instead they were encouraged to stay at home and have as many children as possible. In 1940 Mussolini reviewed a parade of 180 married couples who had produced 1544, the mothers were given gold medals for their service to the nation.

One Day on the River Essay

Elijah has grander and more dangerous dreams. Having been largely acculturated by a residential school upbringing before escaping into the forest to live with Xavier and Niska, he has acquired the dubious skills of public relations and boastfulness as much as the crafts of the hunter. His English, learned from the nuns, is impeccable, and he makes his mark among the men in the trenches as much by the flash of his storytelling as by his murderous midnight prowls in no man’s land. Gradually Elijah becomes imprisoned by two great obsessions: a need for morphine, whose use is rampant up and down the lines, and an insatiable hunger for killing. Some French soldiers suggest that if he really wants to gain respect for all his kills, he should scalp his victims as evidence. He decides to do so, much to Xavier’s disgust. In counterpoint to the exploits of Xavier and Elijah, Boyden interweaves the story of Niska, told as she paddles her wounded nephew back home after the war is over. Niska is part of the sad but admirable remnant of traditional natives who refused to enter the reserves in the 19th century, choosing instead to live by their wits and traditional teachings in the woods. Subject to what modern medicine would call epileptic seizures, Niska is deemed by her tribe to have inherited her father’s skills as a shaman and a windigo-killer. Since windigos manifest themselves in humans who have practiced cannibalism, getting rid of them involves what white society would call murder, and indeed Niska’s father was executed as a murderer by the white courts. The constant crossing of the moral lines between the worldviews of native and white society is one of the many strengths of this fascinating novel. At one point, hunkered down in his sniper’s nest, Xavier indulges himself (and the reader) in a contemplation on the number three, which he sees as an obsession of his white commanders. There’s the front line, the support line, and the reserve line, for starters. There’s the infantry, the cavalry, and the artillery. Off the battlefield, there’s food, then rest, then women. In church, there’s the Father, Son, and Holy Ghost. Not to mention the superstition about lighting three cigarettes with one match, a prime metaphor for courting danger in the Great War. But then Xavier suddenly remembers Niska’s traditional teaching, that those who are dying must walk the three-day road to death, and he wonders â€Å"if we share something, some magic. Maybe it will help me get through all this.† The real war hero, Peggy, makes a brief cameo appearance in the novel, which may not have been a wise choice on the author’s part. The characters of Xavier and Niska and, to a slightly lesser extent, Elijah are full to the brim with life – they’re quite satisfying and believable as they are, and need no further stamp of authentication.

Characterization of Gelatin A biopolymer for Drug Delivery - Free Essay Example

Sample details Pages: 5 Words: 1451 Downloads: 7 Date added: 2019/03/18 Category Analytics Essay Level High school Tags: Characterization Essay Did you like this example? INTRODUCTION Drug Delivery has become an interesting in the present day bringing together Material Science Engineering, Mechanical Engineering, Bio-medical Engineering and Pharm-ology together. This method helps to provide an effective way to use a compound to achieve a therapeutic effect in humans and animals. The technique involves modification of drug release profiles, absorption, distribution and elimination for the benefit of improving product efficacy, safety, as well as patient compliance and convenience. Gelatin is a naturally occurring macromolecular and bio degradable protein that is obtained from skins, tissues and bones of animals. It has high water solubility, non toxicity, high mechanical strength and elasticity in dry state making it a perfect material for drug delivery. There are two kinds of Gelatin. Type A, with isoionic value of 7 to 9, is inferred utilizing solely corrosive pretreatment. Type B, with isoionic value of 4 to 5, is the aftereffect of an antacid pretreatment.[2] Don’t waste time! Our writers will create an original "Characterization of Gelatin A biopolymer for Drug Delivery" essay for you Create order The usual sources of Gelatin are bovine and pig skins and demineralized bones and hooves. This is a cause for problem for people tend to not consume gelatin based medicines due to religious reasons, mad cow disease and social reasons. To solve this, another source of gelatin was experimented for, extraction of Type B gelatin from fresh water fish L. rohita. In this project we look at its extraction, manufacturing of gelatin and the characteristic properties of the type B gelatin obtained.[1] PROCESSING Since there are two sorts of Gelatin, there are two fundamental assembling procedures of Gelatin: Alkaline and corrosive process. The subsequent items can be altogether different as far as piece and physical properties.[4] Acid handled collagen is absorbed weaken corrosive nature of the acid and after that extricated at about pH 4 for gelatin producing. Non-collagenous proteins and mucoproteins of the tissue are isoelectric at this pH and are consequently not so much solvent but rather more promptly coagulated under the extraction conditions. Contaminants which are expelled along these lines rely upon the quality and birthplace of the raw material and the reproducibility of the producers process.[4] When managing the basic procedure, the pretreatment of the collagen requires a drawn out absorbing the soluble arrangements (by and large, immersed lime-water). A decent measure of the pollutions (proteins and mucosubstances) are dissolvable at the oppressed pH and are separated. Gelatins from soluble base process will in general be cleaner than corrosive created gelatin, yet this variety might be because of the assembling process.[4] Moreover to the challenges referenced beforehand, the produce of gelatin is liable to more confusions. For instance the aggregate number of carboxyl gatherings accessible for ionization relies on the extraction technique. Distinctive gelatins can have diverse proportions of acidic and essential gathering in this manner distinctive isoelectric focuses. Charged gatherings impact the cooperations between nearby gelatin atoms, between every particle and the dissolvable and between various parts of a similar atom, as the protein chains are adaptable. The degree of these factors change with pH, and are likewise subject to the aggregate ionic sythesis of the framework in this way an itemized depiction of the dissolvable and additionally that of the gelatin is a necessity.[4] CHARACTERIZATION Sample Preparation Fish scales of L.Rohita having weight of 100-200g were collected at Guntur , Andhra Pradesh , India. The scales were removed using hands, kept in air tight bags and on ice for preservation. Gelatin was extracted using the alkali method. Dried scales were stirred in a solution of 5% NaCl at 30 min room temperature. This step was repeated twice and then the scales were stirred with 4% NaOH to remove the non-collagenous proteins from the scales. To remove lipids from the scales, iso-butyl alcohol was used. This step was repeated three times in a digital linear shaker. The final step was dimineralisation which was done using 0.5N EDTA at a pH of 7.66 for four different time periods of 12h, 2h, 2h and 1h. The scales were then dried on plastic trays and grinded to obtain the gelatin in powder form.[1] Gelatin Yield [1]The gelatin yield is given by the following equation Yield of Gelatin=(Weight of dried Gelatin)/(Dry weight of Fish Scale)?—100 Determination of Gelatin pH To determine the pH of Gelatin, prepare a 1% gelatin solution in distilled water and cool to 25? °C in a water bath. The pH is then measured. UV-vis Spectroscopy Analysis Ultraviolet and Visible absorption spectroscopy is the measurement of the attenuation of a beam of light after it passes through a sample or after reflection from a sample surface. Absorption measurements can be at a single wavelength or over an extended spectral range. UV spectroscopy is used for: Detection of functional groups Detection of Impurities Qualitative analysis Quantitative analysis Single compound without chromophore Drugs with chromophoric reagent Ultraviolet absorbption spectra arise from transition of electron within a molecule from a lower level to a higher level. A molecule absorbs ultraviolet radiation of frequency(V), the electron in that molecule undergoes transition from lower to higher energy level. The energy can be calculated by E_1-E_0=hV The UV-vis absorption spectrum was recorded using a UV vis double beam spectrophotometer in the range of 200-400nm. Fourier transform infrared(FITR) spectroscopy analysis FTIR is a technique based on vibrational spectroscopy. AN infrared spectrum is obtained using fourier transforms. Fourier Transfroms help to represent a range of Sinusodial waves as a single summition function. Presently FITR has replaced the dispersive method as it has a higher signal to noise ratio.[3] The IR enters the interoferometer. It has a beam splitter and 2 mirrors. The beam splitter splits the radiation, One beam strikes a moving mirror and one beam strikes a fixed mirror. The two beams then combine and intract with the sample and then go to the detector. The difference in wave length is plotted and then used to determine a fourier transform.[3] 100 mg of KBr and 2mg of Gelatin was mixed and placed in FITR equipment. FITR was performed at room temperature and measurements were taken. X-Ray diffraction To determine the Crystal structure, X ray diffraction was used. The operating voltage was 45kV and the operating current was at 40mA. The radiation used was Cu K? ±.[1] Scanning Electron Microscopy Scanning Electron Microscopy was used to determine the surface morphology of Gelatin. Gelatin was coated with gold in a vaccum sputter and a photograph was taken.[1] RESULTS AND DISCUSSION Yield of Gelatin The gelatin extracted was yellow and the weight percentage was 24% which is higher than the yield of red tilapia(7.81%) and black tilapia(5.39%)(found in previous studies)[1] Characterization results The UV-vis spectroscopy showed absorption at 224nm, indicating a presence of strong peptide bonds. Absorption at 210-240nm shows the presence of peptide chromophore. Since the operational range was 200-400nm, the results can be considered valid. Refer figure 2.[1] Figure2. UV-vis absorption spectrum of fish scale gelatin FITR measurement made it possible to identify the amino groups present. Also it helped to identify the bonds responsible for the structural and functional stabilization. Amino acids are made of amide bonds which can be identified by the specific amide band that is absorbed at the FITR measurement. [1] Peaks(cm-1) Possible functional bands 3433 Hydrogen bond 1630 Amide-I 1565 Amide-II 1240 Amide-III 1460 Symmetric Bending 1380 Asymmetric Bending Table 1- FITR results of Gelatin Figure 3. FTIR spectrum of gelatin Porosity is determined by Scanning electron microscopy analysis. Porosity characterization is the determination of open pores which determine properties like permeability and the surface area of the porous structure.The microstructure obtained shows that the polymer has an array of hollow cells. Higher density shows greater mechanical strength and the higher porosity shows a better biological environment. The SEM micrograph shows a decent balance between the two.[1] Refer Figure 4. Figure 4. SEM micrograph of gelatin extracted from fish scale The XRD diffractogram shows a sharp peak with low intensity at 2=7? ° and a broad peak at 2=19? °. This is usually assigned to the triple helical crystalline structure of gelatin.[1] Conclusion The study shows that L Rohita is a good source of raw material for Gelatin production. It can be determined that gelatin has the necessary porosity for drug delivery and has a triple helical crystalline structure. The FITR shows it chemical bonds. Thus Fish based Gelatin is an effective source of gelatin for drug delivery. References Merina Paul Das, Suguna PR, Karpuram Prasad, Vijaylakshmi JV, Renuka M. Extraction and characterization of gelatin: a functional biopolymer. Int J Pharm Pharm Sci 2017;9(9):239-242. Gavasane AJ, Pawar HA (2014) Synthetic Biodegradable Polymers Used in Controlled Drug Delivery System: An Overview. Clin Pharmacol Biopharm 3:121.doi:10.4172/2167-065X.1000121 Materials Characterization: Introduction to Microscopic and Spectroscopic Methods by Yang Leng, Second Edition (ISBN No. 978-3-527-33463-6) John Wiley Sons (2013) Felix, Pascal Georges, Characterization and correlation analysis of pharmaceutical gelatin (2003). Graduate Theses and Dissertations. https://scholarcommons.usf.edu/etd/1365